Quite frequently I found I get an error message saying that my profile could not be opened correctly. Which involved going into the folder
And removing the file Web Data which for me was a pain as I use two stage authentication. So I was quite pleased to find when experimenting that simply exiting chrome upon seeing this error and killing all the chrome processes that run in the background after exiting the browser allows me to go back into the browser and it works as normal.
This works in my case and I hope it can work for you too. My experience of this is with Linux however this might work for Windows too. If it does then let me know and I’ll update this post.